Breakthrough scientific research achievements! The new drug AOH1996 can kill all solid tumors.

　　Worldwide, cancer treatment has always been the focus of medical research. Recently, the researchers in the city of hope have made a remarkable breakthrough. They have successfully developed a new drug named AOH1996 by using a target that was previously considered as "an incurable drug", namely proliferating cell nuclear antigen (PCNA). The results of preclinical research show that AOH1996 shows the amazing characteristics of "killing all solid tumors" after testing more than 70 kinds of cancer cells, which has aroused widespread concern in the scientific community.

　　AOH1996 is a highly selective drug, which can kill cancer cells accurately without damaging normal cells, thus achieving a precise attack. In addition, the study also found that AOH1996 not only has the ability to kill cancer cells, but also can improve the therapeutic effect of chemotherapy and bring new hope to cancer patients. In the past two decades, researchers in the city of hope have been working hard to develop AOH1996, an anticancer drug targeting PCNA. Although PCNA was once considered as an "impossible drug" target, scientists overcame the difficulties and successfully developed this potential new drug. AOH1996 prevented cancer cells from dividing and DNA replication, leading to their death, by interfering with the reproductive cycle of cells and selectively killing cancer cells, while healthy cells were protected, showing its characteristics of precise attack.

　　In preclinical studies, AOH1996 showed a good therapeutic effect on a variety of cancer cells, including breast cancer, prostate cancer, brain cancer, ovarian cancer, cervical cancer, skin cancer and lung cancer. In addition, the role of AOH1996 also makes cancer cells more vulnerable to some chemotherapy drugs, such as cisplatin, which also provides new possibilities for combination therapy and the development of new chemotherapy drugs. The Shengnuo family, as the official referral cooperation agency of the City of Hope National Medical Center in China, made a verification to the City of Hope National Medical Center for the first time. It was learned from the hospital that the phase 1 clinical trial was open to the outside world, and eight patients were recruited in the first phase. This means that patients with solid tumors in China also have the opportunity to participate. Researchers in the city of hope said that they have excellent experts in cancer research and basic hardware facilities to promote the transformation of laboratory research results into clinical treatment, and will continue to study the mechanism of AOH1996 and continuously improve the ongoing human clinical trials.

　　The research and development and clinical trial of AOH1996 have brought new hope to cancer patients, and this breakthrough research may have an important impact on future cancer treatment. Scientists in the city of hope will continue to work hard to find new treatment methods and provide better treatment options for patients. If you are interested in the information of all kinds of cancer frontier drugs, technologies or clinical trials around the world, or need to quickly handle the business of going abroad for medical treatment and remote consultation of international authoritative experts in the United States, Japan, Britain and other medically developed countries, please pay attention to private messages and contact me. Let's contribute to the progress of cancer treatment together! Reference source: https://medicalpress.com/news/2023-08-scientists-chemistry-solid-tumors-clinical.html.